[1]徐浩军,邓强△,李中锋,等.仙灵骨葆胶囊联合PVP技术治疗绝经后骨质疏松椎体压缩骨折的临床观察[J].中国中医骨伤科杂志,2018,26(10):20-23.
　XU Haojun,DENG Qiang,LI Zhongfeng,et al.Clinical Observation of Xianlinggubao Capsule Combined with PVP in the Treatment of Postmenopausal Osteoporotic Vertebral Compression Fractures[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2018,26(10):20-23.
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仙灵骨葆胶囊联合PVP技术治疗绝经后骨质疏松椎体压缩骨折的临床观察()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第26卷
期数:
2018年10期
页码:
20-23
栏目:
临床研究
出版日期:
2018-10-10

文章信息/Info

Title:
Clinical Observation of Xianlinggubao Capsule Combined with PVP in the Treatment of Postmenopausal Osteoporotic Vertebral Compression Fractures
文章编号:
1005-0205(2018)10-0020-04
作者:
徐浩军1; 邓强2△; 李中锋2; 彭冉东1; 杨镇源2; 张彦军2; 李军杰1
1甘肃中医药大学(兰州,730000) 2甘肃省中医院
Author(s):
XU Haojun1; DENG Qiang2△; LI Zhongfeng2; PENG Randong1; YANG Zhenyuan2; ZHANG Yanjun2; LI Junjie1
1Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China; 2Gansu Hospital of Traditional Chinese Medicine,Lanzhou 730050,China.
关键词:
绝经后骨质疏松;  仙灵骨葆胶囊;  椎体压缩骨折;  椎体成形术
Keywords:
postmenopausal osteoporosis;  Xianlinggubao capsule;  vertebral compression fracture;  vertebroplasty
分类号:
R683.2
文献标志码:
A
摘要:
目的:观察仙灵骨葆胶囊联合椎体成形术(PVP)对绝经后骨质疏松(PMOP)椎体压缩骨折的临床疗效。方法:选取在甘肃省中医院治疗的绝经后骨质疏松椎体压缩骨折患者98例,根据治疗方法的不同分为观察组49例和对照组49例。两组均行PVP手术,术后口服钙剂治疗,对照组在手术后单纯定期注射依降钙素治疗; 观察组在手术后定期服用中成药仙灵骨葆胶囊和进行注射依降钙素治疗。采用视觉模拟疼痛评分(VAS)及Oswestry功能障碍指数(ODI)对纳入患者腰背部疼痛、活动功能进行评估,对两组患者分别进行随访,观察两组患者在术前、术后3 d、3个月及6个月的VAS,ODI及骨密度的变化。结果:两组患者腰背部疼痛在手术后3 d均得到缓解,观察组与对照组患者在手术前与手术后3 d的VAS和ODI的对比差异均无统计学意义(P>0.05),手术后3个月和6个月的VAS和ODI及术后6个月骨密度的对比,差异均有统计学意义(P<0.05)。结论:仙灵骨葆胶囊联合PVP技术治疗绝经后骨质疏松椎体压缩骨折的疗效显著,降低疼痛评分,改善骨密度,从而大大提高了患者的生活质量,并降低患者椎体再骨折的风险,是绝经后骨质疏松椎体压缩骨折良好的治疗方案。
Abstract:
Objective:To observe the clinical effect of Xianlinggubao capsule combined with vertebroplasty(PVP)on vertebral compression fracture of postmenopausal osteoporosis(PMOP).Methods:All 98 cases of postmenopausal osteoporotic vertebral compression fracture were selected and divided into observation group(49 cases)and control group(49 cases)according to the different treatment methods.Both groups were treated with PVP and oral calcium after operation.The control group was treated with calcitonin injection only at regular intervals after operation.Taking traditional Chinese medicine Xianlinggubao capsule and injecting calcitonin.Visual analogue scale(VAS)and Oswestry dability index(ODI)were used to evaluate the lumbar and dorsal pain and motor function of the patients.The patients in the two groups were followed up.The VAS,ODI and the changes in index and bone mineral density of the patients in the two groups were observed before operation,3 d,3 months and 6 months after operation.Results:There was no significant difference in VAS and ODI between the observation group and the control group 3 d before and after operation(P>0.05).VAS,ODI and bone mineral density in 3 months and 6 months after operation were significantly different(P<0.05).Conclusion:Xianlinggubao capsule combined with PVP technique has a significant effect in the treatment of postmenopausal osteoporotic vertebral compression fractures,through reducing pain scores,improving bone mineral density,thus greatly improving the quality of life of patients,and reducing the risk of vertebral re-fracture.So,it is a good treatment for postmenopausal osteoporotic vertebral compression fractures.

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备注/Memo

备注/Memo:
基金项目:国家中医药管理局国家中医临床研究基地业务建设科研专项课题(JDZX2015039)
△通信作者 E-mail:dengqiang11576@sohu.com
更新日期/Last Update: 2018-10-10